- Offshoot Beer
- Omission Brewing
- One Ten Craft Meatery
- Ozark Mountain Leather
- Only Barnwood Frames
- Operation Space Cat
- Orbelle
- Old Made Quilts
- Originals by Becki
- OldPatterns.com
- Otter Weathervanes
- Off Grid Food Co.
- OMXGraphics
- Old Fashioned Lumber
- Orbit Furniture
- OWO Living
- Oben shops
- Oliverbirch
- Offex
- Office Station
- Olesilk
- Old Europe Duvet
- Outdoor Kitchens & Design
- Ornaments 4 Orphans
- Ornaments for Keeps
- Old Bridgeview Brewing
- Our Dog's World
- One and Only Paper
- Orange House
- Organically Maid
- Ouchie Cap
- Okay Bean
- OnlineBabyGear.com
- Oogie
- Oilladi
- OMG Pretzels
- Oud Beersel
- Old World Anvils
- Old Croc Cheese
- Ojas
- OmniPillow
- Ott Food Products
- OlyKraut
- Olivio
- Obsurvey
- Ori' Zaba's
- One Tough Mother
- Oh Shiny
- Originals Group
- OOLA Distillery
- Osocalis Distillery
- Olmeca Tequila
- Ol' Major Bacon Bourbon
- Owney's Rum
- Orbiloc
- Oranlife
- Only Mine
- Online Insulation
- Our Lawns - Lawn Service & Pressure Washing
- One Touch Spaces
- OPCOM Farm
- Orban's Flowers
- OfficeSuite
- Omega Music
- Ottertex
- Original Herkimer Cheese
- Oscar Newman
- Oili Ruffo
- Olubunmi Creations
- Oakview Collectibles
- Ornament Central
- One Crafty Country Girl
- Oso Famoso
- Old World St. Nicks
- Otaku Arcadia
- Oh You Pretty Things
- On Tap Kitchen
- Olivins
- Olive Oil Etcetera
- Olivo